Although trials used various dosing strategies, members of the BMJ and MAGIC panel recommend a loading dose of 300 mg of clopidogrel followed by 75 mg
The usual dose for clopidogrel is 75mg once a day
72% of reviewers reported a positive effect, while 13% reported a negative effect
Treatment with a loading dose of 300 mg of clopidogrel followed by a daily dose of 75 mg resulted in a 36 percent reduction in the odds of an occluded infarct-related artery or death or recurrent Aspirin + Clopidogrel is used in the treatment of Prevention of heart attack and stroke
94; P < 0
Patients randomly assigned to the clopidogrel–aspirin group received a loading dose of 300 mg of clopidogrel on day 1, followed by a dose of 75 mg per day on days 2 through 90, aspirin at a dose Patients were divided into the high dose group (clopidogrel 150 mg per day + aspirin 100 mg per day over 21 days
In the CSPS
Symptomatic peripheral arterial disease — clopidogrel 75 mg is the preferred treatment
1 The CAPRIE trial (Clopidogrel Versus Aspirin in Patients at Risk for Ischemic Events), published in 1996, showed a
Stroke, or transient ischaemic attack (TIA) Antiplatelet treatment will be managed by specialists
Proton pump inhibitors seem to be the best gastroprotective agents, whereas the benefits of Helicobacter pylori eradication are still unclear
Aspirin and clopidogrel interfere with platelet activation in complementary, but separate pathways
You may need a dose adjustment if you take both medications
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